Saturday, March 29, 2014

Non-nano Zinc Oxide Sunscreen is Best!



I'M FABULOUS COSMETICS use only non-nano zinc oxide because it provides longer-range, more stable and safer UV protection than its mineral counterpart titanium dioxide. Below are just some of the research findings that support this decision. 

There is increasing evidence that long wave ultraviolet (UV) radiation (UVA; 320–400 nm) plays an important role in the pathogenesis of various skin disorders, from polymorphous light eruption to photoaging. 

There is increasing evidence that longwave ultraviolet (UV) radiation (UVA; 320–400 nm) plays an important role in the pathogenesis of photodermatoses such as polymorphous light eruption as well as photoaging. In order to fully understand these detrimental effects it is critical to analyze the photobiological and molecular mechanisms by which UVA radiation affects the function of human skin cells. In this review, our current knowledge about the signal transduction pathway involved in UVA radiation-induced expression of proinflammatory genes relevant to the pathogenesis of polymorphous light eruption will be summarized. In addition, recent studies on the role of mitochondrial DNA mutations in UVA radiation-induced photoaging of human skin will be discussed. For both biological endpoints the UVA radiation-induced generation of singlet oxygen within human skin appears to be of critical importance. These studies are of enormous clinical relevance because they indicate that prevention of the generation of singlet oxygen or inhibition of singlet oxygen-induced signaling pathways may prove to be critical for effective protection of human skin against UVA radiation-induced damage.

UVA radiation induces mitochondrial DNA mutations leading to photoaging as well as other more serious consequences. Studies indicate that zinc oxide provides better protection in the above mentioned 340 to 380 nm range than titanium dioxide. 

In addition to damaging DNA, UVA radiation generates free radicals, which, within human skin also cause allergic reactions and photoaging. 

Sunscreens containing titanium dioxide produced ROS (reactive oxygen species) upon photoexcitation. This is because, contrary to conventional wisdom, TiO2 actually absorbs about 70% of UV light, leading to the generation of the hydroxyl radical. 

In other words, titanium dioxide acts more like chemical absorbers such as oxybenzone or octyl methoxycinnamate than a physical blocker. Zinc oxide, on the other hand, works by scattering and reflecting UV light rather than by absorbing it, and hence is more stable


Because zinc oxide reflects and scatters UV rays rather than absorbing them, it protects more effectively across a broader spectrum than titanium dioxide, without generating free radicals. 

Most people Do not like greasy sunscreen! So I'M FABULOUS COSMETICS decide on a great face powder.