Matrixyl® 3000 - New test A new proof of the efficiency of Matrixyl® 3000, the well-known matrikine based anti-ageing ingredient, is available. This time, its ability to help repair the UV damage-prone papillary dermis has been demonstrated. The papillary dermis, located just under the dermis/epidermis junction (DEJ), is more fragile than the reticular dermis and is intensely affected by photo ageing. Papillary fibroblasts are fundamental to promote epidermal morphogenesis and wound healing that is why papillary dermis repair delivers visible anti-wrinkle benefits. In vivo studies have revealed the positive matrix reinforcing effect of Matrixyl® 3000 by measuring the SLEB density (Subepidermal Low Echogenic Band that corresponds to the papillary dermis). A significant improvement corresponding to a gain in age of 1.8 years is visible in just one month, and confirmed after 2 months: the photo-induced ageing is then delayed by 5.5 years. Another analysis of the papillary dermis by confocal laser microscopy has shown that Matrixyl® 3000 helps reduce the fibre fragmentation and notably supports the reconstruction of the papillary dermal fibre network. This new test confirms the repairing effects of Matrixyl® 3000: promotion of wrinkle smoothing and improvement of skin tone and elasticity. Claiming “Matrixyl inside” on your anti-ageing products makes even more sense. Matrixyl® 3000 Description Matrikines anti-wrinkle complex which helps: - reverse the chronological ageing as attested by the regulation of senescence markers. Ageing skin tends to behave like young skin. - reduce the cutaneous photo damage by restructuring the fragile network of the papillary dermis. Associated terms Mature skin, Anti-wrinkle / Lifting, Regeneration, Matrikines, Protein synthesis, Collagen synthesis, DNA, Glycosaminoglycans, Hyaluronic acid, Macromolecules, SLEB, Photo-ageing, SLEB, papillary dermis, chronological ageing, progerin, senescence markers.